Careers

We are based in Stevenage at the Stevenage Bioscience Catalyst, London at the Royal Free NHS Foundation Trust and Munich and are looking to expand our team.

We provide extraordinary career opportunities for talented individuals, who will have the opportunity to work with highly experienced leaders in science and business with proven track records in building successful businesses. Our success depends on the quality, experience and ambition of the individuals that join our team.

 

LIFE AT FREELINE

If you have what it takes to help build Freeline into a world class gene therapy company and would like to become a part of our team, please contact: recruitment@freelinetx.com

Freeline is an equal opportunity employer committed to a culturally diverse and international team.

Strictly no agencies. Please note that Freeline does not accept speculative applications from recruitment agencies.

U.K. VACANCIES

Development Team Support Assistant – 6 month fixed term role

Job Location:

Stevenage, UK.

Description:

1.0          BACKGROUND FOR THE ROLE

Freeline is a biopharmaceutical company focused on the development and commercialisation of gene therapies for bleeding and other debilitating disorders based on a next-generation AAV gene therapy platform developed by Amit Nathwani, Professor of Haematology at UCL and CSO of Freeline Therapeutics. Freeline is an ambitious clinical-phase biotech company fast progressing several programmes simultaneously with building a state of the art manufacturing platform for AAV.

This individual will support the Chief Development Officer and their organisation to enable them to deliver a broad range of activities enabling the delivery of Freeline’s portfolio and play an integral role in shaping the organisation and its processes.

 2.0          CANDIDATE PROFILE/ROLE

The successful candidate will thrive on multitasking in a busy environment and have excellent people skills. They must have a can-do attitude and proven ability to anticipate business needs and use initiative to find solutions to new problems. They will have a track record of working with dynamic teams, preferably in a pharma/biotech/healthcare environment and have an ability to learn new skills. They must be highly proficient with key IT packages and have very strong organisational skills.

3.0 MAJOR DUTIES AND RESPONSIBILITIES

  • Proactive management of complex calendar for Chief Development Officer (CDO) and their management team
  • Use initiative to develop business processes to enable the Development team to operate efficiently
  • Assist in the preparation of meeting materials, smooth running of meetings and meeting follow-up
  • Assist the CDO and Development team in recruitment, onboarding and ongoing team management, including confidential HR processes
  • Monitor and forecast department travel budget and support CDO in exercising oversight of Departmental expenditure.
  • Work with other Administrative/operations staff and Financial/HR team to facilitate optimal collaboration and synergies
  • Use initiative in Managers absence and work closely with management team to progress departmental objectives.
  • Strict professionalism with all confidential resources and information; consequences of actions are detrimental to the business.

4.0 REQUIREMENTS/QUALIFICATIONS

Basic qualifications:

  • Minimum of five years’ experience in supporting senior Managers as a business support/administrative assistant or office manager
  • Excellent oral and written communication, interpersonal, analytical, and computer skills.
  • Strong organisational and people skills required, including good time management skills.
  • Proven experience in managing complex calendar and travel itineraries
  • Demonstrated expertise in relevant IT tools, including Outlook, Word, PowerPoint, Excel, Skype
  • Demonstrated competence in working with a high degree of confidentiality
  • Proven experience in taking initiative and acting independently with limited direction

Preferred qualifications:

As above plus

  • Experience of budget planning and invoice/PO tracking
  • Experience of recruitment and onboarding
  • Experience in interactions with external companies and a demonstrated ability to facilitate communication, co-ordination and arrange meetings and act as first-line contact

Remuneration Package:

  • Competitive salary, dependent on experience

In return, the successful candidate will enjoy being part of a dynamic, forward-thinking team, with the ability to be involved at the highest level of the development of the company’s strategies and plans. Being part of a small team will ensure minimal bureaucracy in making decisions and executing on these with quality and speed in mind.

The successful candidate will be part of a team that is using innovative and pioneering technology to treat debilitating diseases, which may become the standard of care in the future, experience in developing this technology will be exciting and rewarding.

5.0 LOCATION

Stevenage, UK.

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Lab Manager

Job Location:

SBC, Stevenage

Description:

Freeline Therapeutics (“Freeline”), is a biopharmaceutical company focused on the development of gene therapies for bleeding and other debilitating disorders, based in greater London in the United Kingdom

Freeline was launched in December 2015 with a £25 million Series A financing from Syncona LLP.

The Company’s next-generation AAV gene therapy platform has been developed by Professor Amit Nathwani, Founder and Chief Scientific Officer of Freeline as well as Professor of Haematology at University College London, and it builds on the successful haemophilia B phase I/II trial conducted by him with St. Jude Children’s Research Hospital. The results of the study, published in the New England Journal of Medicine, demonstrated that all ten treated haemophilia B patients showed safe, sustained expression of blood clotting Factor IX from a single treatment.

As part of building our team to drive our portfolio forwards we are seeking a Lab Manager. This person will initially report to the VP Research and will be responsible for supporting the running of the Research Laboratories.  Depending on the starting date, this might include set up of our new facility in Stevenage, supporting moving from our current location to our new location and then ensuring the smooth and safe running of the laboratories.

The successful candidates will join a rapidly growing world-class team and will have the opportunity to play a part in shaping the growth of this exciting new biotechnology Company.

Objectives:

  • Depending on the starting date: Coordinate the set-up of new laboratory and office facilities for the UK team; drive and deliver a number of workstreams including the move from Royal Free to SBC Stevenage
  • Implement and manage business systems for non-GxP compliance, Health & Safety and document management, risk assessments, COSH, and SOPs.
  • Ensure smooth running of the laboratories; ensure facilities are fully operational, equipment maintained, laboratory supplies purchased and managed, any necessary operational systems are implemented.
  • Responsible for ordering, installing and maintaining new and existing equipment in the laboratories.
  • Review consumable ordering practice and negociate price to the best interest of Freeline
  • Co-ordinate applications for appropriate licences such as GMO
  • Co-ordinate and monitor Occupational Health provision
  • In collaboration with scientists, establish and maintain inventories including clinical and non-clinical samples, plasmids, cells and vectors.
  • Monitor, train and inspect Safety practices and Laboratories. Responsible for writing and maintaining Safety lab book up-to-date.
  • Lead the interface with the SBC team to ensure current and future needs met.

Required Qualifications

  • Significant experience as a lab manager
  • Understanding and experience of Laboratory safety.
  • Experience of working in a GxP environment is a plus
  • Experience of lab/office set up/move an advantage
  • Ability to take initiative and take on and drive new challenges
  • Personable and effective communicator.

Interested applicants should submit their applications to Recruitment@freelinetx.com

The application should include a one page letter outlining what makes the applicant suitable for working at Freeline Therapeutics. This letter should be accompanied by a two page C.V.

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GMP Scientist – Manufacturing Operations

Job Location:

Stevenage, UK

Description:

1.0 BACKGROUND FOR THE ROLE

Freeline is a biopharmaceutical company focused on the development and commercialisation of gene therapies for bleeding and other debilitating disorders based on a next-generation AAV gene therapy platform developed by Amit Nathwani, Professor of Haematology at UCL and CSO of Freeline Therapeutics. Freeline is fast progressing several programmes towards clinical investigation simultaneously with building a state of the art manufacturing platform for AAV, and is now establishing a clinical manufacturing facility to ensure we can rapidly translate our novel therapies into the clinic.

We are currently looking for a GMP Scientist to join our growing GMP Manufacturing Operations team to deliver Freelines novel therapies into the clinic. This position provides an exciting opportunity to be play a key role in the team establishing a cutting-edge manufacturing facility which will utilise our proprietary CMC platform for supplying our novel therapies to patients.

2.0 CANDIDATE PROFILE/ROLE

The GMP Scientist will be part of our small team focused on setting up Freelines internal GMP manufacturing capability. The candidate will be responsible for supporting the technology transfer, process validation and the ongoing GMP manufacture required for delivering our clinical viral vector batches.

The successful candidate will have hands-on experience of Biologics Drug Substance GMP manufacturing operations and will be familiar with the practices and procedures involved with GMP manufacturing.

We are looking for an organised, enthusiastic and adaptable individual who is keen to join our exciting and innovative company to deliver our expanding product pipeline to the clinic.

This role will report to the GMP Operations Director.

3.0 MAJOR DUTIES AND RESPONSIBILITIES

  • Be part of the GMP manufacturing operations team responsible for delivering GMP manufacturing batches for clinical studies.
  • Become fully trained in all areas of the manufacturing process as required.
  • Write and review SOPs, batch records, protocols, reports etc. to support GMP manufacture.
  • Ability to identify issues as they occur and report accordingly with all relevant information.
  • To support investigations, OOS, incidents and CAPAs as required.
  • To be part of the team responsible for technology transfer of the process into GMP according to the approved protocols.
  • To work closely with facility and other supporting teams to ensure requirements for manufacture are met.
  • General duties involved in the maintenance of clean room production facilities to GMP standards.
  • General duties involved in the preparation of equipment, materials and facilities ready for GMP manufacture.

4.0 REQUIREMENTS/QUALIFICATIONS

Education

  • BSc degree in biological science.

Experience

  • At least 2 years of hands-on, practical experience in biological drug substance GMP manufacturing operations.
  • A sound understanding of the required industry standards for GMP manufacturing of investigational medicinal products.
  • Hands on experience in the upstream and/or downstream processing for viral vector manufacturing.
  • Experience in one or more of the following areas would be beneficial:
    • Facility operations
    • Equipment qualification and validation.
    • Technology transfer.
    • Process validation.

5.0 LOCATION

Stevenage, UK

6.0 REMUNERATION PACKAGE

  • Competitive salary, dependent on experience
  • Bonus and share options

In return, the successful candidate will enjoy being part of a dynamic, forward thinking team, with the ability shape the Manufacturing and  Supply function for a fast-moving biotech, and play a key role in Freelines mission to develop and use innovative technology to treat debilitating diseases.

Closing Date:

11/02/2018

Job Reference Code:

FRL001/18

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Freeline Platform

Our proprietary and highly optimised platform is aiming to maximise clinical benefit for patients

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Gene Therapy for Haemophilia

Gene therapy has the potential to transform people's lives by safely and continuously delivering clotting proteins to the blood

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Freeline careers

Find out more about life at Freeline and current vacancies in our careers section

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